3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11337 | Fumarate hydratase-IN-1 | Others | |
Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2.2 μM. Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor. | |||
T11336 | Fumarate hydratase-IN-2 sodium salt | Others | |
Fumarate hydratase-IN-2 sodium salt (compound 3) is a cell-permeable and competitive fumarate hydratase inhibitor ( K i =4.5 μM). Fumarate hydratase-IN-2 sodium salt has nutrient-dependent cytotoxicity [1]. | |||
T71901 | MP-1 | ||
MP-1 is a covalent inhibitor of fumarate hydratase (FH) that exhibits cytotoxicity dependent on FH. MP-1 engages a functional cysteine in the Zn-finger domain of the tRNA methyltransferase enzyme TRMT1. |